This IDS Bulletin is the first of two special issues presenting contributions from the event ‘Impact Innovation and Learning: Towards a Research and Practice Agenda for the Future’, organised by IDS in March 2013. The initiative, as well as these two issues, represent a ‘rallying cry’ for impact evaluation to rise to the challenges of a post‐MDG/post‐2015 development agenda. This introduction articulates first what these challenges are, and then goes on to summarise how the contributors propose to meet these challenges in terms of methodological and institutional innovation. Increasingly ambitious development goals, multiple layers of governance and lines of accountability require adequate causal inference frameworks and less ambitious expectations on the span of direct influence single interventions can achieve, as well as awareness of multiple bias types. Institutions need to be researched and become more impact‐oriented and learning‐oriented .